5. Individuals undergoing Hepatitis B immunisation

Obligatory	a) Known Exposure: Must not donate. b) No Known Exposure: Must not donate.
Discretionary	a) Known Exposure: If it is more than 4 months from the date of exposure, samples can be taken for HBV and anti-HBc testing. No donation should be taken. b) No Known Exposure: If it is more than 14 days from the date of the most recent dose of vaccine, accept.
Post-session review of results	a) If the donor is negative for HBV and Anti-HBc, the donor can be accepted. Additional hepatitis B testing is not required for future donations unless the donor discloses a new risk. b) If any of HBsAg, anti-HBc or HBV DNA are positive, refer to Section 1: Active or recovered hepatitis B infection.
See if Relevant	Hepatitis A – 4. Immunisation Immunoglobulin Therapy
Additional Information	Specific HBV immunoglobulin may be used in the management of individuals who have been exposed to hepatitis B. Administration of hepatitis B vaccine can lead to low level reactivity in HBsAg screening assays. For this reason, donors must be deferred until at least 14 days after receiving a dose of vaccine, even if they have not been exposed to HBV. Hepatitis B vaccine is sometimes given in a combined vaccine with hepatitis A vaccine.