21.5: General guidelines for tissue processing Processing must not change the physical properties of the tissue so as to make it unacceptable for clinical use. Processing steps must be v…
21.2: Retrieval 21.2.1: Retrieval times and preliminary storage Tissue retrieval should be completed as soon after death as possible. For eye donation retrieval must be comple…
21.1: General considerations Tissue Establishments should have dedicated processing and storage facilities designed and be operated to prevent contamination, cross-contamination, mislabe…
20.12: References SaBTO (2017) Blood, tissue and cell donor selection criteria report: 2017 (updated 2019)
20.11: Release criteria For allogeneic donors the concluded result of all microbiological assays, with the exception of syphilis and anti-HBc, must be negative for a tissue to be release…
20.10: Archiving of donor samples An archive blood sample should be kept for look-back investigations in the event of an adverse reaction. It is recommended that this should be for a min…
20.9: Autologous tissue donation The designated clinician should decide the policy in relation to the provision of an autologous service. Autologous donors should be tested for the same …
20.8: Follow-up There is a duty of care to the donor and/or donor’s family. For donors who on confirmatory testing have positive or indeterminate results, there should be protocols in pl…
20.7: Deceased donor samples Appropriate mechanisms must be in place to ensure: The secure identification of samples obtained from hospital laboratories. Where there is d…
20.6: Living tissue donor samples All blood samples from living tissue donors must be acquired using positive donor identification by an individual trained to ensure the security of the …
20.5: Donor testing The general principles of microbiological testing and the specific testing requirements for tissue donors are covered in Annex B of the HTA’s Guide to Quality and Saf…
20.4: Tissue-specific donor considerations Reference must be made to the JPAC Donor Selection Guidelines3 document for ages and other specific donor requ…
20.2: Consent Consent must be obtained and documented by appropriately trained professionals competent in the issues and processes of tissue donation. No coercion or inducement to donate…
20.1: General considerations The overall responsibility for applying the policies for the selection and care of tissue donors lies with the Tissue Establishment authorised clinician, who…
19.4: References Statutory Instrument 2007 No. 1523 The Human Tissue (Quality and Safety for Human Application) Regulations 2007, and subsequent amendments. Av…
19.3: Data protection and confidentiality Living donors and families of deceased donors must be told that information relating to the donation will be stored in accordance with the Data …
19.2: Reference documents for tissue banking The advice contained in these guidelines is believed to represent acceptable practice at the time of writing. It is policy to revise these gu…
19.1: Regulatory environment in the UK The whole process of tissue banking is now covered by legislation. The EU Directive on Tissues and Cells and its associated Commission Directives w…
10.6: Look-back investigations Look-back investigations are initiated on recognition that there may have been a risk of transmitting infection from a donor to a recipient. S…
10.4: Investigation of possible bacterial TTI Refer to Chapter 9, section 9.8 for details of laboratory investigations.
10.3: Non-bacterial TTI: identification of possible infectious donations When a decision has been made to conduct an investigation into a reported non-bacterial TTI cas…
9.9: References Statutory Instrument 2005 No. 50. The Blood Safety and Quality Regulations 2005. Available at …
9.8: Investigation of suspected bacterial contamination of blood components Suspected cases of bacterial contamination of blood components may be notified by reports from the hospit…
Order comms for blood components - is it worth it.pdf (771KB)
Implementation of BloodTrack Tx.pdf (945KB)