JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

20.6: Living donor samples

All blood samples from living donors must be acquired using positive donor identification by an individual trained to ensure the security of the sample and supporting documentation. Living donors can be tested by either a single sample taken at the time of donation where testing includes a nucleic acid amplification technique (NAT) or by two samples including a post-quarantine sample where additional NAT testing is not required.

Where only a single sample is tested the ‘donation sample’ must be obtained at the time of donation or, if not possible, within 7 days post-donation.

Where two samples are tested the ‘post-quarantine sample’ is required after an interval of at least 180 days from the date of donation. In these circumstances of repeat testing, the donation sample can be taken up to 30 days prior to and 7 days after donation. When the donation blood sample is taken prior to the date of tissue donation a system must be in place to ensure that the pre-quarantine sample reflects the risk status at the time of donation.

For amnion donation only a maternal sample is required, i.e. a cord blood sample is not required.