17.7: References Flesch BK, Curtis BR, de Haas M, Lucas G, Sachs UJ (2016). Update on the nomenclature of human neutrophil antigens and alleles. Transfusion, 56, 1477–1479.…
17.4: HNA antibody detection methods There are several techniques for the detection of HNA-reactive antibodies. These techniques can be divided into non-specific (where intact g…
17.3: HNA typing methods HNA types should be determined using antibody-based and/or DNA/PCR-based techniques that have been validated in the laboratory. Polyclonal human anti-HN…
17.2: Nomenclature The current nomenclature for HNA and corresponding antibodies is based on epitopes and allelic typing and this must be used for recording granulocyte-specific alloanti…
17.5: Donor testing 17.5.1: HNA typing HNA typing of donors whose granulocytes may be transfused to support HNA-immunised recipients should, wherever possible, be typed twice …
17.6: Patient testing 17.6.1: HNA typing Patients should be typed for HNA following the guidelines for donor HNA typing. A provisional type can be issued on the basis of a phe…