JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

17.3: HNA typing methods

HNA types should be determined using antibody-based and DNA/PCR-based techniques that have been validated in the laboratory.

Polyclonal human anti-HNA antisera used in serological techniques should be well characterised. There is no requirement to use typing antisera that are ABO compatible with the granulocytes since the available evidence suggests that granulocytes either do not express Blood Group A or B antigens or do so very weakly.