JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Valproate

Obligatory

Must not donate

Discretionary

If it is more than seven days since the last dose of valproate, and the reason for therapy does not preclude donation, accept.

Additional Information

Sodium valproate (Epilim®, Episenta®) and the related drugs valproic acid (Depakote®, Convulex®) are anticonvulsant medications used in the treatment of epilepsy. They are also used for treatment of bipolar disorder and as prophylaxis for migraine.


Exposure during pregnancy is a known cause of birth defects. As it is not possible to know whether an individual donation will be transfused to a pregnant woman, donors taking any form of sodium valproate or valproic acid must be deferred until at least one week after stopping treatment.   

Reason for change

This is a new entry.

Donor Information

If you wish to obtain more information regarding a personal medical issue please contact your National Help Line.

Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers.

Update Information

This entry was last updated in:
DSG-WB Edition 203, Release 55.