JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Tissue and Organ Recipients

Obligatory

Must not donate if:
1. At any time:

a) Has needed immunosuppression.

b) Dura mater transplanted.

c) Ocular tissue transplanted.

d) Xenotransplant performed.

2. Since January 1st 1980:
Any allogeneic human tissue or organ transplanted.

Discretionary

a) If an allogeneic tissue or cell transplant was performed before January 1st 1980 and there is no other reason to exclude the donor, accept.

b) If at anytime an autologous tissue, or cells, has been transplanted, accept.

See if Relevant

Immunosuppression
Ocular Tissue Recipient
Prion Associated Diseases
Xenotransplantation

Additional Information

The transfer of tissues or organs between individuals and species has lead to the spread of infection. The above guidelines are intended to minimize these risks.

There is now a concern that this could also happen with vCJD. This is because in the autumn of 2003 a UK recipient of blood, taken from a healthy donor who later developed vCJD, died from vCJD. Since then there have been several cases of infection with the vCJD prion in recipients of blood from donors who have later developed vCJD.
In view of this, people who have received a tissue or organ transplant since 1980, will be excluded from donation in the same way as recipients of transfusion are. This date is before BSE, which is believed to have caused vCJD, was prevalent.

See

Transfusion

Reason for Change

To clarify that transplantation of an autologous tissue, or cells, is not a contra-indication to donation, whether or not the tissue, or cells, were stored prior to transplantation.

Update Information

This entry was last updated in
TDSG-LD Edition 203, Release 34