JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

SRI Publications

The Systematic Review Initiative has so far completed over 120 systematic reviews covering many different aspects of transfusion medicine, including transfusion and COVID-19. Our reviews are all produced using strict methodological criteria in accordance with best evidence-based practice, and have been published in a wide variety of journals, with approximately half appearing in The Cochrane Library. Please view our Publications pages via the left-hand menu for full details of our reviews with full text links.

Recently completed systematic reviews include:

  • Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery
  • Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery
  • Do treatments for anaemia improve tje quality of life and physical function in patients with myelodysplastic syndromes?
  • Interventions for chronic kidney disease in people with sickle cell disease
  • Definitions of massive transfusion in adults with critical bleeding
  • Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery
  • Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia
  • Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures
  • Convalescent plasma or immunoglobulin treatment for people with severe respiratory viral infections due to coronaviruses or influenza
  • Clinical prediction models for blood transfusion in patients undergoing elective surgery
  • Hyperkalaemia following blood transfusion - a systematic review assessing evidence and risks
  • Assessing the risks of haemolysis as an adverse reaction following the transfusion of ABO incompatible plasma-containing components
  • Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19
  • Efficacy and safety of intravenous iron therapy for treating anaemia in critically ill adults (rapid review)
  • Difference in potential harms between whole blood and component blood transfusion in major bleeding (rapid review)

Recent publications:

Gibbs VN, Champaneria R, Sandercock J, Welton NJ, Geneen LJ, Brunskill SJ, Dorée C, Kimber C, Palmer AJ, Estcourt LJ.
Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis.
The Cochrane Database of Systematic Reviews. 2024;1:CD013295.

Lloyd TD, Geneen LJ, Bernhardt K, McClune W, Fernquest SJ, Brown T, Dorée C, Brunskill SJ, Murphy MF, Palmer AJ.
Cell salvage for minimising perioperative allogeneic blood transfusion in adults undergoing elective surgery.
The Cochrane Database of Systematic Reviews. 2023;9:CD001888.

Mo A, Poynton M, Wood E, Shortt J, Brunskill SJ, Doree C, Sandercock J, Saadah N, Luk E, Stanworth SJ, McQuilten Z.
Do anemia treatments improve quality of life and physical function in patients with myelodysplastic syndromes (MDS)? A systematic review.
Blood Reviews. 2023;61:101114.

Roy NB, Carpenter A, Dale-Harris I, Dorée C, Estcourt LJ.
Interventions for chronic kidney disease in people with sickle cell disease.
The Cochrane Database of Systematic Reviews. 2023;8:CD012380.