Appendix III International Haemovigilance Network definition of severe donor adverse events
Conditions which define a case as severe are:
- Hospitalisation: If it was attributable to the complication.
- to preclude permanent damage or impairment of a body function
- to prevent death (life-threatening).
- Symptoms: Causing significant disability or incapacity following a complication of blood donation and persisted for more than a year after the donation (long-term morbidity).
- Death: If it follows a complication of blood donation and the death was possibly, probably or definitely related to the donation.
For the purpose of consistent reporting of SAEDs the UK Blood Transfusion Services have adopted these categories:
- death within 7 days of donation
- hospital admission within 24 hours of donation
- injury resulting in a fracture within 24 hours
- road traffic collision (RTC) within 24 hours of donation
- acute coronary syndrome (ACS) diagnosed within 24 hours of donation
- problems relating to needle insertion persisting for more than a year
- anaphylaxis, haemolysis or air embolism (component donors).