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# Whole blood and components

The Whole Blood and Components Donor Selection Guidelines (WB-DSG) form a constituent part of chapter 3 of the Guidelines for the Blood Transfusion and Tissue Transplantation Services in the UK.

They apply to donors giving whole blood or blood components, including red cells, platelets, plasma and granulocytes, and are for healthcare professionals trained in their use.

## Search

## A to Z list

## View updates

## Additional resources

### Using these guidelines

Learn how to use and apply the WB-DSG

### Source files

Download an offline copy of the WB-DSG

### Drugs and platelet donation

View the index of drugs that can alter platelet function and may require a donor deferral

## Appendices

### Appendix 1

Estimated blood volume for female donors

### Appendix 2

Immunisations

### Appendix 3

Maximum permitted extracorporeal volume

### Appendix 4

Management of post donation illness

## Latest updates

Change number | Title | Updated | Guidelines affected | Release
--- | --- | --- | --- | ---
Change notification number 05-2026 | Title Bleeding Disorder (PDF only, 283KB) | Update date 17 February 2026 | Guidelines affected Whole blood | Release number 79
Change notification number 06-2026 | Title Transgender and Non-Binary Individuals (PDF only, 210KB) | Update date 17 February 2026 | Guidelines affected Whole blood | Release number 79
Change notification number 07-2026 | Title Testosterone Replacement Therapy (PDF only, 339KB) | Update date 17 February 2026 | Guidelines affected Whole blood | Release number 79
Change notification number 26-2025 | Title Weight Loss Medication (PDF only, 296KB) | Update date 28 August 2025 | Guidelines affected Whole blood | Release number 78
Change notification number 27-2025 | Title Deferral after HAV, HBV and JEV vaccines (PDF only, 371KB) | Update date 28 August 2025 | Guidelines affected Whole blood | Release number 78

View all updates to the WB-DSG

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