UK Blood Transfusion & Tissue Transplantation Services
Whole Blood and Components
Donor Selection Guidelines


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Malignancy

Obligatory
Must not donate.
Discretionary
a) If this was a basal cell carcinoma (rodent ulcer) and treatment is completed and all wounds are healed, accept.

b) If this was a cervical carcinoma in situ (cervical intra-epithelial neoplasia - CIN), treatment is completed and a follow up smear did not show abnormal cells, accept.

c) If the potential donor has a non-clonal premalignant condition (e.g. Barrett's oesophagus, Bowen's disease, polyposis coli) that is being regularly monitored, accept.
See if Relevant
Additional Information
Many malignancies spread through the blood stream and by invading surrounding tissues. Viruses that can be spread by blood and tissue donation can also cause some malignancies. For these reasons it is considered safer not to accept blood from people who have had a malignancy.

a) Because basal cell carcinoma (rodent ulcer) does not spread through the blood, people who have had successful treatment may donate.

b) Cervical carcinoma in situ, by definition, has not spread outside of the cervix. Women who have successfully completed treatment for this condition may donate.

c) Premalignant conditions are very common, particularly in older donors. Regular monitoring should prevent donors with invasive malignancy from being accepted. Clonal blood disorders are dealt with differently - see Haematological Disease.
Information
This is a requirement of the Blood Safety and Quality Regulations 2005.
Update Information
This entry was last updated in:
DSG-WB Edition 203, Release 12.
Reason for Change
A 'Discretionary' entry has been added for premalignant conditions.

The 'See if Relevant' entry has been changed.
Donor Information
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