JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Diabetes Mellitus

Also Known As

Sugar diabetes and type I (1) and II (2) diabetes.

Obligatory

Must not donate if:
a) Requires treatment with insulin.

b) Diabetes medication has been altered in the last four weeks.

c) Is having problems with feeling faint, fainting or giddiness.

d) Has suffered from heart failure.

e) Has renal impairment requiring dialysis, the use of erythropoietin or similar drugs, or is either under active investigation or continued follow up for renal impairment.

f) Has required surgery for a blocked or narrowed artery including any type of amputation.

g) Has or has had gangrene.

h) Has or has had ulcers or wounds related to a loss of sensation.

i) Has had a transplant of pancreatic tissue.

Discretionary

a) If diagnosed with pre-diabetes or gestational diabetes but not requiring treatment, accept.

b) If controlled by diet or oral medication or injectable medication other than insulin, e.g. Exenatide (Byetta®) or Liraglutide (Victoza®), that has not been changed in type or dose in the last four weeks, accept.

c) If previous treatment with insulin (including bovine insulin) was stopped more than four weeks ago, accept.

d) If gangrene was not related to diabetes or peripheral vascular disease (e.g. it was due to hypothermia or meningococcal meningitis) and all wounds are fully healed, even if amputation was required, accept.

See if Relevant

Cardiovascular Disease
Central Nervous System Disease
Chiropody
Infection - General
Pregnancy
Tissue and Organ Recipients
Wounds, Mouth and Skin Ulcers

Additional Information

In the UK about one in twenty individuals has diabetes. The majority of cases do not require treatment with insulin. Many people with this type of diabetes (often called type II (2)) are in good health and are fit to donate blood.

It is however important that complications due to diabetes are carefully assessed and, where necessary, donors are excluded from donating (e.g. those at risk of postural hypotension due to autonomic neuropathy, or those at risk of bacteraemia due to unhealed ulcers).

The rationale for not accepting donors on oral medication for diabetes mellitus was reviewed by the Standing Advisory Committee for the Care and Selection of Donors in 2008. It was decided that available data did not support the deferral of all individuals with diabetes that required treatment.

It is a requirement of the Blood Safety and Quality Regulations not to accept donors who are being treated with insulin, or who have received a transplant of human tissue.

 

Diabetic donors should be informed that blood donation will lower their HbA1c (glycated haemoglobin) levels. This blood test is used to monitor their diabetic control. Donors should inform their diabetic team that they are blood donors so this can be taken into account when reviewing HbA1c levels. Blood donation should preferably be performed after HbA1c testing. 


HbA1c decreases under conditions which shorten the life-span of red blood cells (RBC). HbA1c is made when the glucose (sugar) in the body sticks to the RBC. As the body can’t use the sugar properly more of it sticks to the RBC and builds up in the blood. RBC are active for around 3 months. By measuring HbA1c, clinicians are able to get an overall picture of what a patient’s average blood sugar levels have been over a period of weeks/months. For people with diabetes this is important as the higher the HbA1c, the greater the risk of developing diabetes-related complications.

Information

Part of this entry is a requirement of the Blood Safety and Quality Regulations 2005.

Reason for change

Information about the impact of donation on HbA1c testing has been added to the Additional Information section.

Donor Information

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Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers.

Update Information

This entry was last updated in:
DSG-WB Edition 203, Release 56.